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Each sample will beintroduced by the sample number. Many inhaled agents produce sufficientcellular toxicity to cause an increase in the membrane per-meability of the respiratory membrane complex in the lungand other airway linings. This is where the study of A2AR agonistrevealed that there was a benefit (lessen GVHD) to increased stimulation through thisreceptor. Examplesinclude SSRI that are now regarded as dangerous decades later and benzodiazepineswhich now have problems of epidemic iatrogenic addiction

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